Exploring DNA Strand-Displacement Computational Elements
نویسندگان
چکیده
Using the Visual DSD language and tool for describing DNA computational structures, we investigate a gate buffering technique that helps maintaining desired reaction kinetics for unbounded time. We test it by simulation on an oscillator and on an ultrasensitive system.
منابع مشابه
A programming language for composable DNA circuits.
Recently, a range of information-processing circuits have been implemented in DNA by using strand displacement as their main computational mechanism. Examples include digital logic circuits and catalytic signal amplification circuits that function as efficient molecular detectors. As new paradigms for DNA computation emerge, the development of corresponding languages and tools for these paradig...
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DNA strand displacement technique is widely used in DNA programming, DNA biosensors, and gene analysis. In DNA strand displacement, leaky reactions can cause DNA signals decay and detecting DNA signals fails. The mostly used method to avoid leakage is cleaning up after upstream leaky reactions, and it remains a challenge to develop reliable DNA strand displacement technique with low leakage. In...
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متن کاملAbstractions for DNA circuit design
DNA strand displacement techniques have been used to implement a broad range of information processing devices, from logic gates, to chemical reaction networks, to architectures for universal computation. Strand displacement techniques enable computational devices to be implemented in DNA without the need for additional components, allowing computation to be programmed solely in terms of nucleo...
متن کاملSupplementary material for “ Computational design of nucleic acid feedback control circuits ”
6 Visual DSD code for PI controller implementations 13 6.1 Chemical Reaction Network implementation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 6.2 4Domain DNA Strand Displacement implementation . . . . . . . . . . . . . . . . . . . . . . . . . . 16 6.2.1 Initial Conditions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 6.2.2 Reac...
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تاریخ انتشار 2010